PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride.

He, Huan

PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride. [electronic resource] - Investigative ophthalmology & visual science 03 2020 - 54 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-5783

10.1167/iovs.61.3.54 doi


Animals
Anti-Infective Agents, Local--toxicity
Benzalkonium Compounds--toxicity
Calcium-Binding Proteins--metabolism
Cell Count
Cell Line
Cell Survival
Disease Models, Animal
Epithelium, Corneal--drug effects
Fenofibrate--pharmacology
Humans
Hypolipidemic Agents--pharmacology
Immunohistochemistry
Interleukin-6--genetics
Keratin-10--metabolism
Ki-67 Antigen--metabolism
Male
Metaplasia--chemically induced
Mice
Mice, Inbred BALB C
PPAR alpha--agonists
Real-Time Polymerase Chain Reaction
Receptors, G-Protein-Coupled--metabolism
Tumor Necrosis Factor-alpha--genetics