Prodigiosin impairs autophagosome-lysosome fusion that sensitizes colorectal cancer cells to 5-fluorouracil-induced cell death.

Zhao, Chong

Prodigiosin impairs autophagosome-lysosome fusion that sensitizes colorectal cancer cells to 5-fluorouracil-induced cell death. [electronic resource] - Cancer letters 07 2020 - 15-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7980

10.1016/j.canlet.2020.03.010 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Autophagosomes--drug effects
Autophagy--drug effects
Caco-2 Cells
Cell Death--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Colorectal Neoplasms--drug therapy
Fluorouracil--pharmacology
HCT116 Cells
HT29 Cells
Humans
Lysosomes--drug effects
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Recurrence, Local--drug therapy
Prodigiosin--pharmacology