Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma.
Sagers, Jessica E
Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma. [electronic resource] - Scientific reports 03 2020 - 4211 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
2045-2322
10.1038/s41598-020-60156-6 doi
Animals
Benzamides--pharmacology
Dasatinib--pharmacology
Disease Models, Animal
Drug Therapy, Combination
Female
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Morpholines--pharmacology
Neurofibromin 2--genetics
Neuroma, Acoustic--drug therapy
Protein Kinase Inhibitors--pharmacology
Pyrimidines--pharmacology
Receptor, EphA1--metabolism
TOR Serine-Threonine Kinases--antagonists & inhibitors
Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma. [electronic resource] - Scientific reports 03 2020 - 4211 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
2045-2322
10.1038/s41598-020-60156-6 doi
Animals
Benzamides--pharmacology
Dasatinib--pharmacology
Disease Models, Animal
Drug Therapy, Combination
Female
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Morpholines--pharmacology
Neurofibromin 2--genetics
Neuroma, Acoustic--drug therapy
Protein Kinase Inhibitors--pharmacology
Pyrimidines--pharmacology
Receptor, EphA1--metabolism
TOR Serine-Threonine Kinases--antagonists & inhibitors