Anti-leukemic effects of histone deacetylase (HDAC) inhibition in acute lymphoblastic leukemia (ALL) cells: Shedding light on mitigating effects of NF-κB and autophagy on panobinostat cytotoxicity.
Mehrpouri, Mahdieh
Anti-leukemic effects of histone deacetylase (HDAC) inhibition in acute lymphoblastic leukemia (ALL) cells: Shedding light on mitigating effects of NF-κB and autophagy on panobinostat cytotoxicity. [electronic resource] - European journal of pharmacology May 2020 - 173050 p. digital
Publication Type: Journal Article
1879-0712
10.1016/j.ejphar.2020.173050 doi
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis--drug effects
Autophagy--drug effects
Bortezomib--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Drug Synergism
Epigenesis, Genetic--drug effects
G1 Phase--drug effects
Gene Expression Regulation, Leukemic--drug effects
Histone Deacetylase Inhibitors--pharmacology
Humans
NF-kappa B--antagonists & inhibitors
Panobinostat--pharmacology
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Signal Transduction--drug effects
Vincristine--pharmacology
Anti-leukemic effects of histone deacetylase (HDAC) inhibition in acute lymphoblastic leukemia (ALL) cells: Shedding light on mitigating effects of NF-κB and autophagy on panobinostat cytotoxicity. [electronic resource] - European journal of pharmacology May 2020 - 173050 p. digital
Publication Type: Journal Article
1879-0712
10.1016/j.ejphar.2020.173050 doi
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis--drug effects
Autophagy--drug effects
Bortezomib--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Drug Synergism
Epigenesis, Genetic--drug effects
G1 Phase--drug effects
Gene Expression Regulation, Leukemic--drug effects
Histone Deacetylase Inhibitors--pharmacology
Humans
NF-kappa B--antagonists & inhibitors
Panobinostat--pharmacology
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Signal Transduction--drug effects
Vincristine--pharmacology