Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy.
Zheng, Jin
Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy. [electronic resource] - Acta neuropathologica communications 03 2020 - 25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2051-5960
10.1186/s40478-020-00896-8 doi
Adenine Nucleotide Translocator 1--metabolism
Aged
Alzheimer Disease--metabolism
Animals
DNA Damage
DNA Polymerase beta--metabolism
DNA Repair
Disease Models, Animal
Dynamins--metabolism
Frontal Lobe--cytology
Hippocampus--cytology
Homeostasis
Humans
Male
Mice, Transgenic
Microscopy, Electron, Transmission
Microscopy, Immunoelectron
Middle Aged
Mitochondria--metabolism
Neurofibrillary Tangles
Neurons--metabolism
Oxidative Stress
Protein Kinases--metabolism
Sirtuin 3--metabolism
tau Proteins--genetics
Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy. [electronic resource] - Acta neuropathologica communications 03 2020 - 25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2051-5960
10.1186/s40478-020-00896-8 doi
Adenine Nucleotide Translocator 1--metabolism
Aged
Alzheimer Disease--metabolism
Animals
DNA Damage
DNA Polymerase beta--metabolism
DNA Repair
Disease Models, Animal
Dynamins--metabolism
Frontal Lobe--cytology
Hippocampus--cytology
Homeostasis
Humans
Male
Mice, Transgenic
Microscopy, Electron, Transmission
Microscopy, Immunoelectron
Middle Aged
Mitochondria--metabolism
Neurofibrillary Tangles
Neurons--metabolism
Oxidative Stress
Protein Kinases--metabolism
Sirtuin 3--metabolism
tau Proteins--genetics