Characterization of cereblon-dependent targeted protein degrader by visualizing the spatiotemporal ternary complex formation in cells.

Kaji, Tomohiro

Characterization of cereblon-dependent targeted protein degrader by visualizing the spatiotemporal ternary complex formation in cells. [electronic resource] - Scientific reports 02 2020 - 3088 p. digital

Publication Type: Journal Article

2045-2322

10.1038/s41598-020-59966-5 doi


Adaptor Proteins, Signal Transducing--chemistry
Biochemistry--methods
Cell Cycle Proteins--chemistry
Cell Nucleus--chemistry
Cytological Techniques
Drug Design
HEK293 Cells
Humans
Kinetics
Microscopy, Fluorescence
Nuclear Proteins--chemistry
Proteasome Endopeptidase Complex--chemistry
Proteins--chemistry
Proteolysis
Tacrolimus Binding Protein 1A--chemistry
Transcription Factors--chemistry
Ubiquitin-Protein Ligases--chemistry
Ubiquitination