Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.

Cowman, A F

Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Dec 1988 - 9109-13 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0027-8424

10.1073/pnas.85.23.9109 doi


Amino Acid Sequence
Animals
Base Sequence
DNA--genetics
Drug Resistance--genetics
Genes--drug effects
Molecular Sequence Data
Multienzyme Complexes--genetics
Plasmodium falciparum--drug effects
Pyrimethamine--pharmacology
Tetrahydrofolate Dehydrogenase--genetics
Thymidylate Synthase--genetics