Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket.

Yao, Shihua

Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. [electronic resource] - Cell chemical biology 03 2020 - 259-268.e5 p. digital

Publication Type: Journal Article

2451-9448

10.1016/j.chembiol.2020.01.009 doi


Adenosine Triphosphate--antagonists & inhibitors
Allosteric Regulation--drug effects
Carbamoyl-Phosphate Synthase (Ammonia)--antagonists & inhibitors
Dose-Response Relationship, Drug
Enzyme Inhibitors--chemistry
Humans
Hydrolysis--drug effects
Models, Molecular
Molecular Structure
Piperidines--chemistry
Small Molecule Libraries--chemistry
Thiazoles--chemistry