FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer.

Yin, Chunli

FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer. [electronic resource] - Cellular oncology (Dordrecht, Netherlands) Jun 2020 - 395-407 p. digital

Publication Type: Journal Article

2211-3436

10.1007/s13402-020-00494-9 doi


Animals
Carcinoma, Non-Small-Cell Lung--pathology
Cell Cycle Proteins--genetics
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cisplatin--pharmacology
Drug Resistance, Neoplasm--drug effects
Epithelial-Mesenchymal Transition--drug effects
Gene Silencing--drug effects
Humans
Lung Neoplasms--pathology
Mice, Inbred BALB C
Mice, Nude
Microtubule-Associated Proteins--genetics
Neoplasm Invasiveness
Prognosis
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction
TOR Serine-Threonine Kinases--metabolism