Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1.
Zhang, Hai
Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1. [electronic resource] - Cell death & disease 01 2020 - 63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/s41419-020-2227-4 doi
Animals
Antineoplastic Agents--chemistry
Apoptosis--drug effects
Carcinoma, Hepatocellular--genetics
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Nucleus--drug effects
Cell Proliferation--drug effects
Diet
Gene Expression Regulation, Neoplastic--drug effects
Humans
Liver Neoplasms--genetics
Mice, Nude
Phosphorylation--drug effects
Protein Multimerization--drug effects
Protein Transport--drug effects
Protein Tyrosine Phosphatase, Non-Receptor Type 6--metabolism
STAT3 Transcription Factor--metabolism
Signal Transduction--drug effects
Xanthones--chemistry
Xenograft Model Antitumor Assays
Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1. [electronic resource] - Cell death & disease 01 2020 - 63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/s41419-020-2227-4 doi
Animals
Antineoplastic Agents--chemistry
Apoptosis--drug effects
Carcinoma, Hepatocellular--genetics
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Nucleus--drug effects
Cell Proliferation--drug effects
Diet
Gene Expression Regulation, Neoplastic--drug effects
Humans
Liver Neoplasms--genetics
Mice, Nude
Phosphorylation--drug effects
Protein Multimerization--drug effects
Protein Transport--drug effects
Protein Tyrosine Phosphatase, Non-Receptor Type 6--metabolism
STAT3 Transcription Factor--metabolism
Signal Transduction--drug effects
Xanthones--chemistry
Xenograft Model Antitumor Assays