Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice.

Melody, Kevin

Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice. [electronic resource] - Journal of virology 03 2020

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1098-5514

10.1128/JVI.01912-19 doi


Animals
Anti-HIV Agents--pharmacology
Disease Models, Animal
Drug Resistance, Viral--drug effects
Female
HIV Infections--drug therapy
HIV-1--drug effects
Mice
Mutation
Pre-Exposure Prophylaxis--methods
Reverse Transcriptase Inhibitors--pharmacology
Rilpivirine--pharmacology
Vagina--virology
Virus Replication--drug effects
gag Gene Products, Human Immunodeficiency Virus--genetics