Screening for YAP Inhibitors Identifies Statins as Modulators of Fibrosis.

Santos, Daniela M

Screening for YAP Inhibitors Identifies Statins as Modulators of Fibrosis. [electronic resource] - American journal of respiratory cell and molecular biology 04 2020 - 479-492 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1535-4989

10.1165/rcmb.2019-0296OC doi


Acyl Coenzyme A--metabolism
Adaptor Proteins, Signal Transducing--antagonists & inhibitors
Animals
Biomarkers--metabolism
Bleomycin--pharmacology
Cell Cycle Proteins--antagonists & inhibitors
Cell Nucleus--drug effects
Cytoplasm--drug effects
Fibroblasts--drug effects
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Mevalonic Acid--metabolism
Mice
Phosphoproteins--metabolism
Pulmonary Fibrosis--drug therapy
Signal Transduction--drug effects
Simvastatin--pharmacology
Small Molecule Libraries--pharmacology
YAP-Signaling Proteins