Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition.
Zhang, Ziheng
Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition. [electronic resource] - Toxicology in vitro : an international journal published in association with BIBRA Jun 2020 - 104754 p. digital
Publication Type: Journal Article
1879-3177
10.1016/j.tiv.2019.104754 doi
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Curcumin--analogs & derivatives
Endoplasmic Reticulum Stress--drug effects
G2 Phase Cell Cycle Checkpoints--drug effects
Humans
Membrane Potential, Mitochondrial--drug effects
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Squamous Cell Carcinoma of Head and Neck--drug therapy
TOR Serine-Threonine Kinases--antagonists & inhibitors
Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition. [electronic resource] - Toxicology in vitro : an international journal published in association with BIBRA Jun 2020 - 104754 p. digital
Publication Type: Journal Article
1879-3177
10.1016/j.tiv.2019.104754 doi
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Curcumin--analogs & derivatives
Endoplasmic Reticulum Stress--drug effects
G2 Phase Cell Cycle Checkpoints--drug effects
Humans
Membrane Potential, Mitochondrial--drug effects
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Squamous Cell Carcinoma of Head and Neck--drug therapy
TOR Serine-Threonine Kinases--antagonists & inhibitors