Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis.

Wang, Mei-Jen

Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis. [electronic resource] - Cells 12 2019

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2073-4409

10.3390/cells9010022 doi


Animals
Ataxia Telangiectasia Mutated Proteins--metabolism
Cell Survival--drug effects
Cells, Cultured
DNA Damage
Disease Models, Animal
Dopaminergic Neurons--cytology
Drug Synergism
Gene Knockdown Techniques--methods
Humans
Male
Parkinson Disease--etiology
Peroxiredoxins--genetics
Primary Cell Culture
Rats
Rotenone--adverse effects
Signal Transduction--drug effects
Tumor Suppressor Protein p53--metabolism
Tumor Suppressor Proteins--metabolism