Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides.
Diller, David J
Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides. [electronic resource] - Molecules (Basel, Switzerland) Dec 2019
Publication Type: Journal Article
1420-3049
10.3390/molecules24244586 doi
Binding Sites
Drug Design
Ligands
Models, Molecular
Molecular Conformation
Molecular Docking Simulation
Molecular Dynamics Simulation
Mutation
Peptides, Cyclic--chemistry
Protein Binding
Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors
Quantitative Structure-Activity Relationship
Tumor Suppressor Protein p53--antagonists & inhibitors
Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides. [electronic resource] - Molecules (Basel, Switzerland) Dec 2019
Publication Type: Journal Article
1420-3049
10.3390/molecules24244586 doi
Binding Sites
Drug Design
Ligands
Models, Molecular
Molecular Conformation
Molecular Docking Simulation
Molecular Dynamics Simulation
Mutation
Peptides, Cyclic--chemistry
Protein Binding
Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors
Quantitative Structure-Activity Relationship
Tumor Suppressor Protein p53--antagonists & inhibitors