Sanguinarine inhibits epithelial-mesenchymal transition via targeting HIF-1α/TGF-β feed-forward loop in hepatocellular carcinoma.
Su, Qi
Sanguinarine inhibits epithelial-mesenchymal transition via targeting HIF-1α/TGF-β feed-forward loop in hepatocellular carcinoma. [electronic resource] - Cell death & disease 12 2019 - 939 p. digital
Publication Type: Journal Article
2041-4889
10.1038/s41419-019-2173-1 doi
Animals
Benzophenanthridines--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Hypoxia--drug effects
Cell Movement--drug effects
Cell Proliferation--drug effects
Epithelial-Mesenchymal Transition--drug effects
Hep G2 Cells
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Isoquinolines--pharmacology
Liver Neoplasms--drug therapy
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Signal Transduction--drug effects
Transforming Growth Factor beta--metabolism
Tumor Burden--drug effects
Xenograft Model Antitumor Assays
Sanguinarine inhibits epithelial-mesenchymal transition via targeting HIF-1α/TGF-β feed-forward loop in hepatocellular carcinoma. [electronic resource] - Cell death & disease 12 2019 - 939 p. digital
Publication Type: Journal Article
2041-4889
10.1038/s41419-019-2173-1 doi
Animals
Benzophenanthridines--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Hypoxia--drug effects
Cell Movement--drug effects
Cell Proliferation--drug effects
Epithelial-Mesenchymal Transition--drug effects
Hep G2 Cells
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Isoquinolines--pharmacology
Liver Neoplasms--drug therapy
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Signal Transduction--drug effects
Transforming Growth Factor beta--metabolism
Tumor Burden--drug effects
Xenograft Model Antitumor Assays