C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4.

Sheikh-Zeineddini, Negar

C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4. [electronic resource] - European journal of pharmacology Mar 2020 - 172821 p. digital

Publication Type: Journal Article

1879-0712

10.1016/j.ejphar.2019.172821 doi


Antineoplastic Agents--pharmacology
Antineoplastic Combined Chemotherapy Protocols
Apoptosis--drug effects
Autophagy--drug effects
Caspase 3--metabolism
Cell Line, Tumor
DNA-Binding Proteins--antagonists & inhibitors
Drug Discovery
Drug Resistance, Neoplasm
Gene Expression Regulation--drug effects
Humans
NIMA-Interacting Peptidylprolyl Isomerase--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Signal Transduction
Thiazoles--pharmacology
Transcription Factors--antagonists & inhibitors
Vincristine--pharmacology