Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein.

Woodring, Jennifer L

Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein. [electronic resource] - Journal of medicinal chemistry 01 2020 - 205-215 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1520-4804

10.1021/acs.jmedchem.9b01244 doi


Aniline Compounds--chemical synthesis
Animals
Antiviral Agents--chemical synthesis
Binding Sites--drug effects
Female
Influenza A virus--chemistry
Mice, Inbred BALB C
Molecular Docking Simulation
Molecular Structure
Nucleocapsid Proteins
Protein Binding
Protein Multimerization--drug effects
RNA-Binding Proteins--metabolism
Static Electricity
Structure-Activity Relationship
Thiazoles--chemical synthesis
Viral Core Proteins--metabolism