Induction of demyelination by a temperature-sensitive mutant of the coronavirus MHV-A59 is associated with restriction of viral replication in the brain.

Koolen, M J

Induction of demyelination by a temperature-sensitive mutant of the coronavirus MHV-A59 is associated with restriction of viral replication in the brain. [electronic resource] - The Journal of general virology Mar 1987 - 703-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1317

10.1099/0022-1317-68-3-703 doi


Animals
Brain--microbiology
DNA Replication
Hepatitis, Viral, Animal--pathology
Mice
Microscopy, Electron
Murine hepatitis virus--genetics
Mutation
Myelin Sheath--ultrastructure
Spinal Cord--microbiology
Temperature
Virulence
Virus Replication