Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress.

Byrne, Frances L

Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress. [electronic resource] - Redox biology 01 2020 - 101374 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

2213-2317

10.1016/j.redox.2019.101374 doi


Benzoquinones--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Doxorubicin--pharmacology
Glycolysis--drug effects
Humans
Lactams, Macrocyclic--pharmacology
Mitochondria--drug effects
Naphthoquinones--pharmacology
Oxidative Stress--drug effects
Oxygen Consumption--drug effects
Phenotype
Small Molecule Libraries--pharmacology
Vitamin K 3--pharmacology