Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats.

Aulinger, Benedikt A

Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats. [electronic resource] - American journal of physiology. Endocrinology and metabolism 02 2020 - E189-E197 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1522-1555

10.1152/ajpendo.00298.2019 doi


Animals
Dipeptidyl Peptidase 4--metabolism
Glucagon-Like Peptide 1--administration & dosage
Glucose--pharmacology
Glucose Clamp Technique
Injections, Intravenous
Insulin Secretion--drug effects
Insulin-Secreting Cells--drug effects
Jugular Veins
Liver--metabolism
Male
Portal Vein
Rats
Rats, Long-Evans