Aspirin enhances cisplatin sensitivity of resistant non-small cell lung carcinoma stem-like cells by targeting mTOR-Akt axis to repress migration.
Khan, Poulami
Aspirin enhances cisplatin sensitivity of resistant non-small cell lung carcinoma stem-like cells by targeting mTOR-Akt axis to repress migration. [electronic resource] - Scientific reports 11 2019 - 16913 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-019-53134-0 doi
Antineoplastic Agents--pharmacology
Aspirin--pharmacology
Carcinoma, Non-Small-Cell Lung
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cisplatin--pharmacology
Drug Resistance, Neoplasm--drug effects
Drug Synergism
Epithelial-Mesenchymal Transition--drug effects
Humans
Lung Neoplasms
Neoplastic Stem Cells--drug effects
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--metabolism
Transcription Factor RelA--metabolism
p300-CBP Transcription Factors--metabolism
Aspirin enhances cisplatin sensitivity of resistant non-small cell lung carcinoma stem-like cells by targeting mTOR-Akt axis to repress migration. [electronic resource] - Scientific reports 11 2019 - 16913 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-019-53134-0 doi
Antineoplastic Agents--pharmacology
Aspirin--pharmacology
Carcinoma, Non-Small-Cell Lung
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cisplatin--pharmacology
Drug Resistance, Neoplasm--drug effects
Drug Synergism
Epithelial-Mesenchymal Transition--drug effects
Humans
Lung Neoplasms
Neoplastic Stem Cells--drug effects
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--metabolism
Transcription Factor RelA--metabolism
p300-CBP Transcription Factors--metabolism