Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling.

Eyre, Rachel

Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. [electronic resource] - Nature communications 11 2019 - 5016 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-1723

10.1038/s41467-019-12807-0 doi


Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Bone Neoplasms--drug therapy
Breast Neoplasms--drug therapy
Cell Line, Tumor
Female
HEK293 Cells
Humans
Interleukin-1beta--metabolism
MCF-7 Cells
Mice, Inbred BALB C
Mice, Inbred NOD
Mice, Knockout
Mice, Nude
Mice, SCID
Neoplastic Stem Cells--drug effects
Sulfasalazine--administration & dosage
Tumor Microenvironment--drug effects
Wnt Signaling Pathway
Xenograft Model Antitumor Assays