Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling.
Eyre, Rachel
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. [electronic resource] - Nature communications 11 2019 - 5016 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-1723
10.1038/s41467-019-12807-0 doi
Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Bone Neoplasms--drug therapy
Breast Neoplasms--drug therapy
Cell Line, Tumor
Female
HEK293 Cells
Humans
Interleukin-1beta--metabolism
MCF-7 Cells
Mice, Inbred BALB C
Mice, Inbred NOD
Mice, Knockout
Mice, Nude
Mice, SCID
Neoplastic Stem Cells--drug effects
Sulfasalazine--administration & dosage
Tumor Microenvironment--drug effects
Wnt Signaling Pathway
Xenograft Model Antitumor Assays
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. [electronic resource] - Nature communications 11 2019 - 5016 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-1723
10.1038/s41467-019-12807-0 doi
Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Bone Neoplasms--drug therapy
Breast Neoplasms--drug therapy
Cell Line, Tumor
Female
HEK293 Cells
Humans
Interleukin-1beta--metabolism
MCF-7 Cells
Mice, Inbred BALB C
Mice, Inbred NOD
Mice, Knockout
Mice, Nude
Mice, SCID
Neoplastic Stem Cells--drug effects
Sulfasalazine--administration & dosage
Tumor Microenvironment--drug effects
Wnt Signaling Pathway
Xenograft Model Antitumor Assays