Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types.
Klutchko, S
Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types. [electronic resource] - Journal of medicinal chemistry Oct 1986 - 1953-61 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm00160a026 doi
Angiotensin-Converting Enzyme Inhibitors
Animals
Isoquinolines--chemical synthesis
Male
Molecular Conformation
Quinapril
Rats
Rats, Inbred Strains
Structure-Activity Relationship
Sulfhydryl Compounds--pharmacology
Tetrahydroisoquinolines
Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types. [electronic resource] - Journal of medicinal chemistry Oct 1986 - 1953-61 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm00160a026 doi
Angiotensin-Converting Enzyme Inhibitors
Animals
Isoquinolines--chemical synthesis
Male
Molecular Conformation
Quinapril
Rats
Rats, Inbred Strains
Structure-Activity Relationship
Sulfhydryl Compounds--pharmacology
Tetrahydroisoquinolines