Control of Antibody Impurities Induced by Riboflavin in Culture Media During Production.

Wallace, Alison

Control of Antibody Impurities Induced by Riboflavin in Culture Media During Production. [electronic resource] - Journal of pharmaceutical sciences 01 2020 - 566-575 p. digital

Publication Type: Journal Article

1520-6017

10.1016/j.xphs.2019.10.039 doi


Animals
Antibodies, Monoclonal--biosynthesis
Antibody Affinity
Binding, Competitive
CHO Cells
Cell Culture Techniques
Cricetulus
Culture Media--metabolism
Drug Contamination
Hydrophobic and Hydrophilic Interactions
Immunoglobulin G--biosynthesis
Light
Protein Binding
Protein Processing, Post-Translational
Recombinant Proteins--metabolism
Riboflavin--metabolism
Tryptophan--chemistry