On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors.

Morschhauser, Franck

On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors. [electronic resource] - Molecular cancer therapeutics 02 2020 - 468-478 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

1538-8514

10.1158/1535-7163.MCT-19-0466 doi


Biopsy--methods
Cell Line, Tumor
Female
Humans
Lymphoma--drug therapy
Male
Neoplasms--drug therapy
Phosphatidylinositol 3-Kinases--pharmacology
Pyrimidines--pharmacology
Quinazolines--pharmacology