Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72.

Laflamme, Carl

Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72. [electronic resource] - eLife 10 2019

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2050-084X

10.7554/eLife.48363 doi


Amyotrophic Lateral Sclerosis--diagnosis
Animals
Antibodies, Monoclonal--chemistry
Biomarkers--metabolism
C9orf72 Protein--genetics
CRISPR-Cas Systems
Cell Line, Tumor
Frontotemporal Dementia--diagnosis
Gene Editing
Gene Expression
HEK293 Cells
Humans
Immunohistochemistry--standards
Lysosomes--genetics
Mice
Mice, Inbred C57BL
Mice, Transgenic
Osteoblasts--metabolism
Phagosomes--genetics
RAW 264.7 Cells