Induced pluripotent stem cells-derived neurons from patients with Friedreich ataxia exhibit differential sensitivity to resveratrol and nicotinamide.

Georges, Pauline

Induced pluripotent stem cells-derived neurons from patients with Friedreich ataxia exhibit differential sensitivity to resveratrol and nicotinamide. [electronic resource] - Scientific reports 10 2019 - 14568 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-019-49870-y doi


Apoptosis
Cell Survival
Cells, Cultured
Drug Design
Fibroblasts--cytology
Friedreich Ataxia--drug therapy
Gene Expression Profiling
Humans
Induced Pluripotent Stem Cells--cytology
Iron-Binding Proteins--genetics
Karyotyping
Neurons--cytology
Niacinamide--pharmacology
Phenotype
Resveratrol--pharmacology
Translational Research, Biomedical
Frataxin