Phase II study of temozolomide and topotecan (TOTEM) in children with relapsed or refractory extracranial and central nervous system tumors including medulloblastoma with post hoc Bayesian analysis: A European ITCC study.

Le Teuff, Gwénaël

Phase II study of temozolomide and topotecan (TOTEM) in children with relapsed or refractory extracranial and central nervous system tumors including medulloblastoma with post hoc Bayesian analysis: A European ITCC study. [electronic resource] - Pediatric blood & cancer 01 2020 - e28032 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

1545-5017

10.1002/pbc.28032 doi


Adolescent
Adult
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Bayes Theorem
Central Nervous System Neoplasms--drug therapy
Cerebellar Neoplasms--drug therapy
Child
Child, Preschool
Drug Resistance, Neoplasm--drug effects
Female
Follow-Up Studies
Humans
Infant
Male
Medulloblastoma--drug therapy
Neoplasm Recurrence, Local--drug therapy
Neuroectodermal Tumors, Primitive--drug therapy
Prognosis
Salvage Therapy
Survival Rate
Temozolomide--administration & dosage
Topotecan--administration & dosage
Young Adult