Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules.

Rimbault, Charlotte

Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules. [electronic resource] - Nature communications 10 2019 - 4521 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-1723

10.1038/s41467-019-12528-4 doi


Animals
Antibodies--chemistry
COS Cells
Chlorocebus aethiops
Disks Large Homolog 4 Protein--antagonists & inhibitors
Drug Design
Epitope Mapping
Models, Molecular
PDZ Domains
Peptide Library
Peptides--chemistry
Protein Binding
Protein Engineering
Protein Interaction Maps--drug effects
Recombinant Proteins--metabolism