The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle.

Neame, Samah

The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America 10 2019 - 20736-20742 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1909458116 doi


Animals
Astrocytes--cytology
Glycine--metabolism
Hippocampus--cytology
Long-Term Potentiation
Mice
Mice, Inbred C57BL
Mice, Knockout
Neurons--cytology
Phosphoglycerate Dehydrogenase--genetics
Racemases and Epimerases--physiology
Receptors, N-Methyl-D-Aspartate--genetics
Serine--metabolism
Synapses--physiology