The NKCC1 antagonist bumetanide mitigates interneuronopathy associated with ethanol exposure in utero.

Skorput, Alexander Gj

The NKCC1 antagonist bumetanide mitigates interneuronopathy associated with ethanol exposure in utero. [electronic resource] - eLife 09 2019

Publication Type: Journal Article; Research Support, N.I.H., Extramural

2050-084X

10.7554/eLife.48648 doi


Alcohol Drinking--adverse effects
Animals
Bumetanide--administration & dosage
Cerebral Cortex--drug effects
Disease Models, Animal
Female
Fetal Alcohol Spectrum Disorders--physiopathology
GABAergic Neurons--drug effects
Mice
Prefrontal Cortex--drug effects
Pregnancy
Pregnancy Complications--physiopathology
Sodium Potassium Chloride Symporter Inhibitors--administration & dosage
Solute Carrier Family 12, Member 2--metabolism
Treatment Outcome
gamma-Aminobutyric Acid--metabolism