Development of an LC-MS/MS method for quantitative analysis of Chlorogenic acid in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor.
Yang, Fen
Development of an LC-MS/MS method for quantitative analysis of Chlorogenic acid in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor. [electronic resource] - Journal of pharmaceutical and biomedical analysis Jan 2020 - 112809 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Validation Study
1873-264X
10.1016/j.jpba.2019.112809 doi
Anticarcinogenic Agents--administration & dosage
Area Under Curve
China
Chlorogenic Acid--administration & dosage
Chromatography, High Pressure Liquid--methods
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Stability
High-Throughput Screening Assays--methods
Humans
Injections, Intramuscular
Neoplasms--blood
Quinic Acid--administration & dosage
Reproducibility of Results
Sensitivity and Specificity
Tandem Mass Spectrometry--methods
Development of an LC-MS/MS method for quantitative analysis of Chlorogenic acid in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor. [electronic resource] - Journal of pharmaceutical and biomedical analysis Jan 2020 - 112809 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Validation Study
1873-264X
10.1016/j.jpba.2019.112809 doi
Anticarcinogenic Agents--administration & dosage
Area Under Curve
China
Chlorogenic Acid--administration & dosage
Chromatography, High Pressure Liquid--methods
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Stability
High-Throughput Screening Assays--methods
Humans
Injections, Intramuscular
Neoplasms--blood
Quinic Acid--administration & dosage
Reproducibility of Results
Sensitivity and Specificity
Tandem Mass Spectrometry--methods