A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model.
Son, Sumin
A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model. [electronic resource] - Journal of drug targeting 04 2020 - 419-427 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1029-2330
10.1080/1061186X.2019.1669042 doi
Animals
Antibodies, Monoclonal--pharmacology
CHO Cells
CTLA-4 Antigen--metabolism
Cell Line
Cell Proliferation--drug effects
Cricetulus
Disease Models, Animal
Female
Humans
Immune Checkpoint Inhibitors--pharmacology
Immunotherapy--methods
Leukocytes, Mononuclear--drug effects
Male
Mice
Mice, Inbred BALB C
Mice, Inbred NOD
Neoplasms--drug therapy
Programmed Cell Death 1 Receptor--metabolism
Protein Binding--drug effects
T-Lymphocytes--drug effects
A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model. [electronic resource] - Journal of drug targeting 04 2020 - 419-427 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1029-2330
10.1080/1061186X.2019.1669042 doi
Animals
Antibodies, Monoclonal--pharmacology
CHO Cells
CTLA-4 Antigen--metabolism
Cell Line
Cell Proliferation--drug effects
Cricetulus
Disease Models, Animal
Female
Humans
Immune Checkpoint Inhibitors--pharmacology
Immunotherapy--methods
Leukocytes, Mononuclear--drug effects
Male
Mice
Mice, Inbred BALB C
Mice, Inbred NOD
Neoplasms--drug therapy
Programmed Cell Death 1 Receptor--metabolism
Protein Binding--drug effects
T-Lymphocytes--drug effects