Analysis of the Mechanisms of Action of Naphthoquinone-Based Anti-Acute Myeloid Leukemia Chemotherapeutics.

Lee, Michelle H

Analysis of the Mechanisms of Action of Naphthoquinone-Based Anti-Acute Myeloid Leukemia Chemotherapeutics. [electronic resource] - Molecules (Basel, Switzerland) Aug 2019

Publication Type: Journal Article; Review

1420-3049

10.3390/molecules24173121 doi


Cell Differentiation--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Drug Screening Assays, Antitumor
HL-60 Cells
Humans
Leukemia, Myeloid, Acute--drug therapy
MAP Kinase Signaling System--drug effects
Membrane Potential, Mitochondrial--drug effects
Naphthoquinones--pharmacology
Reactive Oxygen Species--metabolism