A systems pharmacokinetic/pharmacodynamic model for concizumab to explore the potential of anti-TFPI recycling antibodies.

Yuan, Dongfen

A systems pharmacokinetic/pharmacodynamic model for concizumab to explore the potential of anti-TFPI recycling antibodies. [electronic resource] - European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Oct 2019 - 105032 p. digital

Publication Type: Journal Article

1879-0720

10.1016/j.ejps.2019.105032 doi


Animals
Antibodies, Monoclonal--pharmacokinetics
Antibodies, Monoclonal, Humanized--pharmacokinetics
Blood Coagulation--drug effects
Endosomes--metabolism
Haplorhini
Hemophilia A--metabolism
Humans
Lipoproteins--metabolism
Models, Biological
Rabbits