Cyclooxygenase-2 Induced the β-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E

Guan, Pei-Pei

Cyclooxygenase-2 Induced the β-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E [electronic resource] - Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 10 2019 - 1255-1268 p. digital

Publication Type: Journal Article

1878-7479

10.1007/s13311-019-00770-z doi


Alzheimer Disease--drug therapy
Amyloid beta-Peptides--metabolism
Animals
Apoptosis--drug effects
Cell Line, Tumor
Cyclooxygenase 2--biosynthesis
Cyclooxygenase Inhibitors--administration & dosage
Dinoprostone--biosynthesis
Female
Mice
Mice, Inbred C57BL
Mice, Transgenic
Neurons--metabolism
Nitrobenzenes--administration & dosage
Prostaglandin D2--analogs & derivatives
Sulfonamides--administration & dosage
Up-Regulation--drug effects