12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation.

Chung, Eun Joo

12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation. [electronic resource] - Radiation research 08 2019 - 367-379 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1938-5404

10.1667/RR15356.1 doi


Alveolar Epithelial Cells--pathology
Animals
Arachidonate 12-Lipoxygenase--genetics
Cellular Senescence--radiation effects
Female
Gene Expression Regulation, Enzymologic--radiation effects
Interleukin-13--biosynthesis
Interleukin-4--biosynthesis
Macrophages--cytology
Mice
Mice, Inbred C57BL
Radiation Pneumonitis--enzymology