Defibrotide enhances fibrinolysis in human endotoxemia - a randomized, double blind, crossover trial in healthy volunteers.

Schoergenhofer, Christian

Defibrotide enhances fibrinolysis in human endotoxemia - a randomized, double blind, crossover trial in healthy volunteers. [electronic resource] - Scientific reports 07 2019 - 11136 p. digital

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-019-47630-6 doi


Adult
Blood Coagulation--drug effects
C-Reactive Protein--metabolism
Cross-Over Studies
Cytokines--metabolism
Double-Blind Method
Endotoxemia--drug therapy
Female
Fibrinolysin--metabolism
Fibrinolysis--drug effects
Fibrinolytic Agents--therapeutic use
Healthy Volunteers
Humans
Lipopolysaccharides--administration & dosage
Male
Polydeoxyribonucleotides--therapeutic use
Young Adult
alpha-2-Antiplasmin--metabolism