IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.

Channappanavar, Rudragouda

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. [electronic resource] - The Journal of clinical investigation 07 2019 - 3625-3639 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1558-8238

10.1172/JCI126363 doi


Animals
Cell Separation
Coronavirus Infections--immunology
Cytokines--immunology
Female
Flow Cytometry
Gene Expression Profiling
Hematopoietic Stem Cells--cytology
Humans
Inflammation
Interferon-beta--immunology
Lung--immunology
Macrophages--immunology
Male
Mice
Mice, Inbred BALB C
Middle East Respiratory Syndrome Coronavirus--pathogenicity
Monocytes--immunology
Neutrophils--immunology
Signal Transduction
Virus Replication