A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.

Shen, Zhou

A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence. [electronic resource] - The Journal of biological chemistry 09 2019 - 13606-13618 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.RA119.009713 doi


Alphacoronavirus--genetics
Animals
Betacoronavirus
Host Microbial Interactions--genetics
Humans
Middle East Respiratory Syndrome Coronavirus--genetics
Porcine epidemic diarrhea virus--genetics
Protein Biosynthesis
RNA-Dependent RNA Polymerase--genetics
Severe acute respiratory syndrome-related coronavirus--genetics
Swine
Synapsins--metabolism
Transmissible gastroenteritis virus--genetics
Viral Nonstructural Proteins--genetics
Virulence
Virus Replication--genetics