Pseudolaric acid B inhibits PAX2 expression through Wnt signaling and induces BAX expression, therefore promoting apoptosis in HeLa cervical cancer cells.

Guan, Defeng

Pseudolaric acid B inhibits PAX2 expression through Wnt signaling and induces BAX expression, therefore promoting apoptosis in HeLa cervical cancer cells. [electronic resource] - Journal of gynecologic oncology Sep 2019 - e77 p. digital

Publication Type: Journal Article

2005-0399

10.3802/jgo.2019.30.e77 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Survival--drug effects
Diterpenes--pharmacology
Female
HeLa Cells
Humans
Mitochondria--drug effects
PAX2 Transcription Factor--antagonists & inhibitors
Uterine Cervical Neoplasms--drug therapy
Wnt Signaling Pathway--physiology
bcl-2-Associated X Protein--metabolism