Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility.

Stowers, Ryan S

Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility. [electronic resource] - Nature biomedical engineering 12 2019 - 1009-1019 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2157-846X

10.1038/s41551-019-0420-5 doi


Breast Neoplasms--pathology
Cell Culture Techniques
Cell Line, Tumor
Chromatin
Epithelial Cells
Epithelium--pathology
Extracellular Matrix--metabolism
Female
Humans
Mechanotransduction, Cellular
Phenotype
Sp1 Transcription Factor
Transcription Factors
Tumor Microenvironment