Effect of Itraconazole or Rifampin on Itacitinib Pharmacokinetics When Administered Orally in Healthy Subjects.

Barbour, April M

Effect of Itraconazole or Rifampin on Itacitinib Pharmacokinetics When Administered Orally in Healthy Subjects. [electronic resource] - Journal of clinical pharmacology 12 2019 - 1641-1647 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-4604

10.1002/jcph.1484 doi


Administration, Oral
Adult
Area Under Curve
Cytochrome P-450 CYP3A--metabolism
Cytochrome P-450 CYP3A Inducers--therapeutic use
Cytochrome P-450 CYP3A Inhibitors--therapeutic use
Drug Interactions--physiology
Female
Healthy Volunteers
Humans
Itraconazole--therapeutic use
Male
Middle Aged
Protein Kinase Inhibitors--pharmacokinetics
Rifampin--therapeutic use
Young Adult