Addition of sirolimus to standard cyclosporine plus mycophenolate mofetil-based graft-versus-host disease prophylaxis for patients after unrelated non-myeloablative haemopoietic stem cell transplantation: a multicentre, randomised, phase 3 trial.

Sandmaier, Brenda M

Addition of sirolimus to standard cyclosporine plus mycophenolate mofetil-based graft-versus-host disease prophylaxis for patients after unrelated non-myeloablative haemopoietic stem cell transplantation: a multicentre, randomised, phase 3 trial. [electronic resource] - The Lancet. Haematology Aug 2019 - e409-e418 p. digital

Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study

2352-3026

10.1016/S2352-3026(19)30088-2 doi


Aged
Cyclosporine--therapeutic use
Disease-Free Survival
Drug Therapy, Combination
Female
Graft vs Host Disease--mortality
HLA Antigens--metabolism
Hematopoietic Stem Cell Transplantation--adverse effects
Humans
Immunosuppressive Agents--therapeutic use
Male
Middle Aged
Mycophenolic Acid--therapeutic use
Proportional Hazards Models
Recurrence
Sirolimus--therapeutic use
Survival Rate
Transplantation, Homologous
Treatment Outcome
Whole-Body Irradiation