Acute bilirubin ditaurate exposure attenuates ex vivo platelet reactive oxygen species production, granule exocytosis and activation.

Pennell, Evan Noel

Acute bilirubin ditaurate exposure attenuates ex vivo platelet reactive oxygen species production, granule exocytosis and activation. [electronic resource] - Redox biology 09 2019 - 101250 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2213-2317

10.1016/j.redox.2019.101250 doi


Adolescent
Adult
Alprostadil--pharmacology
Antioxidants--pharmacology
Bilirubin--analogs & derivatives
Blood Platelets--cytology
Cell Survival--drug effects
Cytoplasmic Granules--drug effects
Exocytosis--drug effects
Female
Gene Expression--drug effects
Humans
Male
Membrane Potential, Mitochondrial--drug effects
Middle Aged
Mitochondria--drug effects
P-Selectin--genetics
Peptide Fragments--antagonists & inhibitors
Platelet Activation--drug effects
Platelet Aggregation--drug effects
Platelet Glycoprotein GPIIb-IIIa Complex--genetics
Primary Cell Culture
Reactive Oxygen Species--agonists
Taurine--analogs & derivatives