A novel SGLT2 inhibitor, SU-011, improves glycaemic control in rodents without the risk of hypoglycaemia and weight gain.

Huang, Fei

A novel SGLT2 inhibitor, SU-011, improves glycaemic control in rodents without the risk of hypoglycaemia and weight gain. [electronic resource] - The Journal of pharmacy and pharmacology Sep 2019 - 1393-1399 p. digital

Publication Type: Journal Article

2042-7158

10.1111/jphp.13130 doi


Animals
Benzhydryl Compounds--chemistry
Blood Glucose--drug effects
C-Reactive Protein
Diabetes Mellitus, Experimental--blood
Glucosides--chemistry
HEK293 Cells
Humans
Interleukin-1beta--blood
Male
Mice
Peptide Fragments--blood
Pyrans--chemistry
Sodium-Glucose Transporter 1--antagonists & inhibitors
Sodium-Glucose Transporter 2--metabolism
Sodium-Glucose Transporter 2 Inhibitors--pharmacology
Streptozocin
Tumor Necrosis Factor-alpha--blood