Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.

Johnson, Eachan O

Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes. [electronic resource] - Nature 07 2019 - 72-78 p. digital

Publication Type: Journal Article

1476-4687

10.1038/s41586-019-1315-z doi


Antitubercular Agents--classification
DNA Gyrase--metabolism
Drug Discovery--methods
Drug Resistance, Microbial
Folic Acid--biosynthesis
Gene Deletion
Microbial Sensitivity Tests--methods
Molecular Targeted Therapy
Mycobacterium tuberculosis--cytology
Mycolic Acids--metabolism
Reproducibility of Results
Small Molecule Libraries--classification
Substrate Specificity
Topoisomerase II Inhibitors--isolation & purification
Tryptophan--biosynthesis
Tuberculosis--drug therapy