Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis.

Carella, Antonella

Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis. [electronic resource] - International journal of cancer 01 2020 - 373-387 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0215

10.1002/ijc.32520 doi


5-Methylcytosine--analogs & derivatives
Animals
Biopsy
Brain Neoplasms--genetics
Carcinogenesis--genetics
Cell Line, Tumor
DNA Methylation
Dioxygenases--genetics
Down-Regulation
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Glioblastoma--genetics
Histone Code--genetics
Humans
Mice
Prognosis
RNA, Messenger--metabolism
Survival Analysis
Xenograft Model Antitumor Assays