Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.

Boru, Getachew

Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations. [electronic resource] - Investigative ophthalmology & visual science 06 2019 - 2474-2480 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1552-5783

10.1167/iovs.18-26452 doi


Blotting, Western
Cell Line, Tumor
Cohort Studies
DNA Mutational Analysis
GTP-Binding Protein alpha Subunits--genetics
GTP-Binding Protein alpha Subunits, Gq-G11--genetics
Humans
Immunohistochemistry
Melanoma--enzymology
Mitogen-Activated Protein Kinases--metabolism
Mutation
Plasmids
Polymorphism, Restriction Fragment Length
Sequence Analysis, DNA
Signal Transduction
Transfection
Uveal Neoplasms--enzymology
Uveal Melanoma